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folder Alkenes (2)
folder Dehydration of Alcohols (2)
folder E1 Elimination (2)
folder Dehydrohalogenation of Alkyl Halides (2)
folder E2 Mechanism (1)


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Articles
document Elimination Reactions
Elimination reactions are important as a method for the preparation of alkenes. The term "elimination" describes the fact that a small molecule is lost during the process. A 1,2-elimination indicates that the atoms that are lost come from adjacent C atoms. The two most important methods...
01 Aug, 2011 Comments: 0
document Substitution and Elimination as Competing Reactions
Often times, multiple reaction pathways compete with one another depending on the conditions and the materials used in a specific reaction.  The example of substitution and elimination is our first model of such competing reactions.  By understanding the pathways that occur for both...
05 Jul, 2011 Comments: 0
document Zaitsev Rule
In many cases elimination reactions may proceed to give alkenes that are isomeric but with one formed in excess of the other (i.e. a major product). Zaitsev's Rule, based on experimental observations of the dehydration of alcohols, expresses the preference for eliminations to give the highly...
01 Aug, 2011 Comments: 0
document Carbocation Rearrangements
Carbocations are prone to rearrangement via 1,2-hyride or 1,2-alkyl shifts provided it generates a more stable carbocation. For example: Notice that the "predicted" product is only formed in 3% yield, and that products with a different...
12 Feb, 2012 Comments: 0
document Stereoselectivity Examples of Elimination Reactions
Eliminations often favor the more stable trans-product over the cis-product and favor more substituted alkenes (Zaitsev's Rule).  See the examples below
04 Sep, 2012 Comments: 0
document Solvent Effects
In general terms, the choice of solvent can have a significant effect on the performance of a reaction. Factors to considering when choosing a solvent for a specific reaction are: solubility : need to get reagents in the same phase, the molecules need to collide to react ...
11 May, 2012 Comments: 0
document Leaving Groups
 A leaving group , LG, is an atom (or a group of atoms) that is displaced as stable species taking with it the electrons in the bond that were connecting it to the rest of the molecule. Typically the leaving group is an anion (e.g. Cl-) or a neutral molecule...
13 May, 2012 Comments: 0

Department of Chemistry & Chemical Biology