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document Dehydration of Alcohols
The dehydration of alcohols is both regioselective and stereoselective.  Regioselectively, explained by the Zaitsev Rule, the major product is always the more highly substituted alkene (alkene stability is increased by inductive and hyperconjugative electron donation to the electron deficient...
27 May, 2011 Comments: 0
document Zaitsev Rule
In many cases elimination reactions may proceed to give alkenes that are isomeric but with one formed in excess of the other (i.e. a major product). Zaitsev's Rule, based on experimental observations of the dehydration of alcohols, expresses the preference for eliminations to give the highly...
01 Aug, 2011 Comments: 0

Department of Chemistry & Chemical Biology